College of Natural and Social Sciences
Department of Chemistry & Biochemistry
Office
ASCB122D
Phone
323-343-2353
Email
ywang184@calstatela.edu
Associate Professor
Research Interests:
Analytical Chemistry, Nanoscale electrochemistry, Scanning probe microscopy, Plasmonics based imaging and sensing techniques, Single entity analysis, Parkinson's Disease, Environmental Sciences
Teaching:
CHEM 3500 Quantitative Analysis
CHEM 4510 Advanced Analytical Chemistry: Optical Spectroscopy
CHEM 4520 Advanced Analytical Chemistry: Analytical Separations and Mass Spectrometry
CHEM 4530 Advanced Analytical Chemistry: Electrochemistry and Surface Techniques
CHEM 5000 Interdisciplinary Discoveries in Chemistry and Biochemistry
Educational Background:
Postdoctoral Research Associate, Biodesign Institute, Arizona State University, 2013-2016
Ph.D. in Chemistry, The City University of New York, New York, NY, 2007-2013
B. S. in Materials Chemistry, Peking University, Beijing, China, 2002-2006
Selected Publications:
(Please see Google Scholar Citation for a full list of publications, student authors from CSULA are highlighted in bold)
- A. Garcia, C. Dhoj, S. Groysman, K. Wang, S. Vo, A. Anguiano, T. Tran, D. Jiang and Y. Wang* "Prussian blue nanofilm-sensitized plasmonic electrochemical microscopy for spatially resolved detection of the localized delivery of hydrogen peroxide" Sensor Actuator Rep 2024, 8, 100218, DOI: 10.1016/j.snr.2024.100218
- C. Dhoj, A. Garcia, A. Manasyan, M. Benavides, D. Abou Abbas, C. Toscano, E. Porter, and Y. Wang* "Scanning Ion Conductance Microscopy Reveals Differential Effect of PM2.5 Exposure on A549 Lung Epithelial and SH-SY5Y Neuroblastoma Cell Membranes" Anal. Bioanal. Chem. 2023, 415, 4557–4567, DOI: 10.1007/s00216-023-04690-y
- S. G. Guillen, J. Parres-Gold, A. Ruiz, E. Lucsik, B. Dao, T. K. L. Hang, M. Chang, A. O. Garcia, Y. Wang*, and F. Tian* "pH-Responsive Metal–Organic Framework Thin Film for Drug Delivery"Langmuir 2022, 38 (51), 16014–16023
- C. Feng, M. Flores, C. Dhoj, A. Garcia, S. Belleca, D. Abou Abbas, J. Parres-Gold, A. Anguiano, E. Porter, and Y. Wang* "Observation of Alpha-Synuclein Pre-Formed Fibrils Interacting with SH-SY5Y Neuroblastoma Cells Membranes Using Scanning Ion Conductance microscopy" ACS Chem. Neurosci., 2022, 13 (24), 3547-3553
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B. A. Beadell, A. Chieng, K. R Parducho, Z. Dai, S. Ho, G. Fujii, Y. Wang, E. Porter* "Nano- and Macroscale Imaging of Cholesterol Linoleate and Human Beta Defensin 2-Induced Changes in Pseudomonas aeruginosa Biofilms" Antibiotics, 2021, 10 (11), 1279
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A. Garcia, K. Wang, F. Bedier, M. Benavides, Z. Wang, S. Wang, Y. Wang* "Plasmonic Imaging of Electrochemical Reactions at Individual Prussian Blue Nanoparticles" Front. Chem., 2021, 9, 718666
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A. Garcia, S. Wang, N. Tao, X. Shan*, Y. Wang* "Plasmonic Imaging of Oxidation and Reduction of Single Gold Nanoparticles and Their Surface Structural Dynamics" ACS Sens. 2020, 6 (2), 502-507
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J. Parres-Gold, A. Chieng, S. Wong Su, Y. Wang* “Real-Time Characterization of Cell Membrane Disruption by α-Synuclein Oligomers in Live SH-SY5Y Neuroblastoma Cells” ACS Chem. Neurosci., 2020, 11 (17), 2528-2534
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K. R Parducho, B. Beadell, T. Ybarra, M. Bush, E. Escalera, A. T. Trejos, A. Chieng, M. Mendez, C. Anderson, H. Park, Y. Wang, W. Lu, E. Porter* “The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Pseudomonas aeruginosa Without Compromising Metabolic Activity” Front Immunol, 2020, 11, 805
- M. Chang, G. Morgan, F. Bedier, A. Chieng, P. Gomez, S. Raminani, Y. Wang* “Recent advances in nanosensors built with pre-pulled glass nanopipettes and their applications in chemical and biological sensing” J. Electrochem. Soc., 2020, 167 (3), 037533
- Q. Liu, X. Wang*, A. Benedict, L. Janibekyan, S. Wong Su, Y. Wang*, F. Zhou* “Surface Plasmon Resonance Coupled with Potential-Step Chronoamperometry: Theory and Applications for Quantitative Measurements of Electrodeposited Thin Films”. Electroanalysis, 2019, 31, 1-8.
- A. Chieng, M. Chiang, K. Triloges, M. Chang and Y. Wang* “Recent progress in the studies of electrochemical interfaces by surface plasmon resonance spectroscopy and microscopy”, Curr. Opin. Electrochem. 2019, 13, 94.
- S. Wong Su, A. Chieng, J. Parres-Gold, M. Chang, Y. Wang* “Real-time determination of aggregated alpha-synuclein induced membrane disruption at neuroblastoma cells using scanning ion conductance microscopy” Faraday Discuss., 2018, 210, 131
- Y. Wang, D. Wang, M. V. Mirkin “Resistive-pulse and Rectification Sensing with Glass and Carbon Nanopipettes” invited article for Proc. R. Soc. A, 2017, 473, 20160931
- Y. Wang, X. Shan, S. Wang, N. Tao “Plasmonic Imaging of Surface Electrochemistry of Single Gold Nanowires”, J. Am. Chem. Soc., 2017, 139, 1376
- Y. Wang, X. Shan, N. Tao “Emerging Tools for Studying Single Entity Electrochemistry”, Faraday Discuss, 2016, 193, 9
- Y. Wang, X. Shan, S. Wang, N. Tao, P. Y. Blanchard, Y. Yu, K. Hu, and M. V. Mirkin “Imaging Local Electric Field Distribution by Plasmonic Impedance Microscopy” Anal. Chem. 2016, 88, 1547
- Y. Wang, X. Shan, F. Cui, J. Li, S. Wang, N. Tao, “Electrochemical Reactions in Sub-femtoliter-Droplets Studied with Plasmonics-based Electrochemical Current Microscopy” Anal. Chem. 2014, 87, 494
- Y. Wang, K. Kececi, M. V. Mirkin “Electron Transfer/Ion Transfer Mode of the Scanning Electrochemical Microscope (SECM)”, Chem. Sci., 2013 ,4, 3606
- Y. Wang, K. Kececi, M. V. Mirkin, V. Mani, N. Sardesai and J. F. Rusling “Resistive-Pulse Measurements with Nanopipettes: Detection of Au Nanoparticles and Nanoparticle-Bound Anti-peanut IgY”, Chem. Sci., 2013 ,4, 655
- Y. Wang, J.-M. Noel, J. Velmurugan, W. Nogala, M. V. Mirkin, С. Lu, M. G. Collignonl, F. Lemaître and C. Amatore “Nanoelectrodes for Determination of Reactive Oxygen and Nitrogen Species inside Biological Cells” Proc. Nat. Acad. Sci., 2012, 109, 11534.
- Y. Wang, T. Kakiuchi, F. Shigematsu and M. V. Mirkin “Kinetics of Ion Transfer at the Ionic Liquid/Water Nanointerface” J. Am. Chem. Soc., 2010, 132, 16945.
- Y. Wang, J. Velmurugan and M. V. Mirkin, P. J. Rodgers, J. Kim and S.Amemiya “Kinetic Study of Rapid Transfer of Tetraethylammonium at the 1,2-Dichloroethane/Water Interface by Nanopipet Voltammetry of Common Ions” Anal. Chem., 2010, 82, 77.
Funding:
NSF CCI (subcontract, 2022-2025)
NSF CAREER (PI, 2021-2026)
NIH Research Enhancement Award (R15, PI, 2020-2024)
NSF-Major Research Instrumentation (PI, 2018-2021)
NSF CREST (Co-PI, 2022-2027)
La Kretz Environment Endowment (PI, 2018-2019)
NSF-PREM (seed grant PI, 2018-2019)
CSUPERB New Investigator Grant (PI, 2017-2019)
CSU RSCA (PI)